The 13th Conference of the Czech Neuroscience Society
November 24 – 25, 2021, Prague, Czech Republic
CONFERENCE PROGRAM
WEDNESDAY, NOVEMBER 24, 2021
08:30 – 09:00 Poster setup
09:00 – 09:10 Opening of the Conference
09:10 – 09:50 Plenary lecture – James Fawcett: Regeneration of axons in the central nervous system
09:50 – 10:10 Coffee Break
10:10 – 11:40 Session 1 – Glial cells, extracellular matrix and regeneration: Chairman – Josef Syka
10:10 – 10:25 V. Brezováková: Alzheimer’s disease iPSC derived astrocytes display altered Ca2+ signalling and ability to degrade tau in vitro
10:25 – 10:40 K. Karova: PI3Kδ stimulates axonal growth after spinal cord injury
10:40 – 10:55 H. Pivonkova: Heterogeneity of oligodendrocyte precursor cells in health and disease
10:55 – 11:10 J. Ruzicka: The role of brain extracellular matrix sulfation epitopes in aging
11:10 – 11:25 P. Honzlova: Circadian clock in microglia and its interaction with mouse brain oscillators
11:25 – 11:40 J.C.F. Kwok: Oral treatment of 4-methylumbelliferone attenuates perineuronal nets and enhances neuroplasticity
11:40 – 12:25 Methodological symposium – Preclinical neuroimaging
11:40 – 11:55 O. Novak: The new in vivo optophysiological tools with cellular resolution invite us far beyond the action potentials
11:55 – 12:10 D. Hadraba: Introduction to BioImaging Technology for Neuroscience at CZBI facilities
12:10 – 12:25 A. Rizzi: Dual color imaging in freely-behaving rodents using a head-mountable one photon miniscope
12:25 – 14:00 Poster session I. and lunch
14:00 – 15:30 Session 2 – Circadian, pain, sensory, and cellular neuroscience II: Chairman – Ladislav Vyklický
14:00 – 14:15 M. Heles: Interaction between TRPV1 and opioid system in opioid analgesia and opioid-induced hyperalgesia.
14:15 – 14:30 P. Greiner: Deciphering responses of the fetal suprachiasmatic nuclei to the rhythmic maternal signals using omics approach
14:30 – 14:45 M. Kralikova: KCTD16 modulates short-term plasticity of synaptic transmission in CA1 pyramidal neurons
14:45 – 15:00 B. Hruskova: Tinnitus-related changes in GABA-B receptor function in the dorsal cochlear nucleus of mice
15:00 – 15:15 Z. Bures: Influence of Assymetric Hearing Loss on Peripheral and Central Auditory Processing Abilities
15:15 – 15:30 O. Profant: Functional changes in the auditory cortex caused by presbycusis and tinnitus.
15:30 – 16:00 Coffee Break
16:00 – 17:00 Session 3 – Circadian, pain, sensory, and cellular neuroscience II: Chairwoman – Alena Sumová
16:00 – 16:15 V. Vyklicky: Conformational rearrangement of the NMDA receptor amino-terminal domain during activation and allosteric modulation
16:15 – 16:30 T. Smejkalova: Endogenous neurosteroids pregnanolone and pregnanolone sulfate potentiate presynaptic glutamate release through distinct mechanisms
16:30 – 16:45 S. Sivcev: Positive allosteric modulation of recombinant and endogenously expressed P2X receptors by steroidal amides
16:45 – 17:00 P. Mrozkova: Effect of soluble Fractalkine on modulation of nociceptive transmission at spinal cord level
THURSDAY, NOVEMBER 25, 2021
08:30 – 09:00 Poster setup
09:00 – 09:40 Plenary lecture 2 – Jiri Palecek: How do we perceive temperature, touch and pain. TRPV1, TRPM8 and PIEZO receptors
09:40 – 10:00 Coffee Break
10:00 – 12:00 Session 4 – Circuit and behavioral neuroscience: Chairman – Karel Ježek, Jakub Otáhal
10:00 – 10:15 D. Kuncicka: One Trial Trace Escape Reaction (OTTER) Task for Rats: Focused on Incidental Encoding
10:15 – 10:30 K. Korvasova: Glutamatergic neurons in the medial septum generate persistent firing and induce locomotion
10:30 – 10:45 D. Spicarova: Inflammation switches the mechanism of 20:4-NAPE-induced inhibition of nociceptive synaptic transmission in the spinal cord
10:45 – 11:00 H. Janickova: Nicotinic acetylcholine receptors expressed by cholinergic interneurons control neuronal activity and striatal-based behavior
11:00 – 11:15 D. Levcik: Hippocampal encoding of positions of inaccessible visual objects
11:15 – 11:30 J. Svoboda: Neural substrate of avoidance of a dynamic object in rats
11:30 – 11:45 M. Balastik: Unique role of CRMP2 isoforms in microtubule dynamics, axon guidance and brain development
11:45 – 12:00 S. Leemburg: Evolution of hippocampal place cell representations in slowly morphing environments
12:00 – 14:00 Poster session II. and lunch
14:00 – 16:00 Session 5 – Diseases – from genes to behavior: Chairman: Aleš Stuchlík, Martin Balaštík
14:00 – 14:15 L. Vyklicky: Functional and pharmacological consequences of de novo nonsense and frame-shift mutations in the GRIN2A and GRIN2B C-terminal domain found in neurodevelopmental disorders
14:15 – 14:30 A. Balik: Evidence for the association between the intronic haplotypes of ionotropic glutamate receptors and schizophrenia
14:30 – 14:45 L. Valihrach: Decoding the transcriptional response to ischemic stroke in young and aged mouse brain
14:45 – 15:00 D. Bohaciakova: Setting up the model of Alzheimer’s disease using cerebral organoids
15:00 – 15:15 M. Candelas Serra: Functional assessment of mice carrying a de novo missense mutation in the GRIN2B associated with ASD
15:15 – 15:30 K. Semenovykh: Effects of the postnatal methamphetamine administration on the basal ganglia and related structures in female rats
15:30 – 15:45 E. Patrono: The role of optogenetic stimulations in PreFrontal Cortex and Ventral Hippocampus on an acute MK-801 model of SCZ-like cognitive inflexibility
15:45 – 16:00 P. Jiruska: High-frequency oscillations in a model of epilepsy due to focal cortical dysplasia type II
16:00 – 16:30 End of the Conference – Announcement of the prizes